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Whilst minimal-depend MBL hardly ever progresses to CLL, higher-depend MBL progresses to CLL requiring therapy in a charge of one% to 2% per year. Significant-count MBL is distinguished from Rai 0 CLL dependant on whether the B-cell count is previously mentioned or down below 5 × 109/L. Even though men and women with both large-count MBL and CLL R